Associated Departments

Veterinary Science

Scholars@UK

Prevalence of anti-N. caninum and anti-N. hughesi antibodies in horses and associated risk factors in two selected equine zones of Punjab, Pakistan

Talib, M. T., Nasir, A., Kashif, M., Rahman, A., Rehman, A. U., Akbar, H., Nadeem, A., Howe, D. K. & Azam, M. N., Feb 2025, In: Veterinary Parasitology: Regional Studies and Reports. 58, 101211.

Research output: Contribution to journal › Article › peer-review

Characterization of SnROP9, a rhoptry protein homologue of Sarcocystis neurona that is expressed in lifecycle stages lacking rhoptry organelles

Jegatheesan, A., Micciche, M., Ngo, J., Bradley, P. J., Howe, D. K. & Dangoudoubiyam, S., May 2025, In: International Journal for Parasitology. 55, 6, p. 327-337 11 p.

Research output: Contribution to journal › Article › peer-review

Tropical Density Estimation of Phylogenetic Trees

Yoshida, R., Barnhill, D., Miura, K. & Howe, D., 2024, (Accepted/In press) In: IEEE/ACM Transactions on Computational Biology and Bioinformatics. p. 1-10 10 p.

Research output: Contribution to journal › Article › peer-review

Temporal gene expression during asexual development of the apicomplexan Sarcocystis neurona

Dangoudoubiyam, S., Norris, J. K., Namasivayam, S., de Paula Baptista, R., do Nascimento, N. C., Camp, J., Schardl, C. L., Kissinger, J. C. & Howe, D. K., Jun 2024, In: mSphere. 9, 6

Research output: Contribution to journal › Article › peer-review

Systemic Caryospora-like coccidiosis in a clutch of hatchling red-eared slider turtles (Trachemys scripta elegans)

Falconnier, N., Warshaw, M., Wellehan, J. F. X., Childress, A. L., Howe, D. K., Taylor, H., Langohr, I. M., Ard, M. B., Paulsen, D. B., Sasaki, E., Mitchell, M. S. & Carossino, M., Jan 2024, In: Veterinary Pathology. 61, 1, p. 95-108 14 p.

Research output: Contribution to journal › Article › peer-review

Equine Protozoal Myeloencephalitis

MacKay, R. J. & Howe, D. K., Aug 2022, In: Veterinary Clinics of North America - Equine Practice. 38, 2, p. 249-268 20 p.

Research output: Contribution to journal › Review article › peer-review

Transcriptional dynamics in the protozoan parasite Sarcocystis neurona and mammalian host cells after treatment with a specific inhibitor of apicomplexan mRNA polyadenylation

Hunt, A. G., Howe, D. K., Brown, A. & Yeargan, M., Oct 2021, In: PLoS ONE. 16, 10 October, e0259109.

Research output: Contribution to journal › Article › peer-review

Pathologic and immunohistochemical findings in an outbreak of systemic toxoplasmosis in a mob of red kangaroos

Carossino, M., Bauer, R., Mitchell, M. A., Cummings, C. O., Stöhr, A. C., Wakamatsu, N., Harper, K., Langohr, I. M., Schultz, K., Mitchell, M. S., Howe, D. K. & Balasuriya, U. B. R., May 2021, In: Journal of Veterinary Diagnostic Investigation. 33, 3, p. 554-565 12 p.

Research output: Contribution to journal › Article › peer-review

Expression of Toxoplasma gondii genes in the closely-related apicomplexan parasite Neospora caninum

Howe, D. K., Mercier, C., Messina, M. & Sibley, L. D., May 1997, In: Molecular and Biochemical Parasitology. 86, 1, p. 29-36 8 p.

Research output: Contribution to journal › Article › peer-review

Selective inhibition of Sarcocystis neurona calcium-dependent protein kinase 1 for equine protozoal myeloencephalitis therapy

Ojo, K. K., Dangoudoubiyam, S., Verma, S. K., Scheele, S., DeRocher, A. E., Yeargan, M., Choi, R., Smith, T. R., Rivas, K. L., Hulverson, M. A., Barrett, L. K., Fan, E., Maly, D. J., Parsons, M., Dubey, J. P., Howe, D. K. & Van Voorhis, W. C., Dec 1 2016, In: International Journal for Parasitology. 46, 13-14, p. 871-880 10 p.

Research output: Contribution to journal › Article › peer-review

Seroepidemiology of Sarcocystis neurona and Neospora hughesi infections in domestic donkeys (Equus asinus) in Durango, Mexico

Alvarado-Esquivel, C., Howe, D. K., Yeargan, M. R., Alvarado-Esquivel, D., Alfredo Zamarripa-Barboza, J. & Dubey, J. P., 2017, In: Parasite. 24, 2, 24.

Research output: Contribution to journal › Article › peer-review

Neospora caninum antibodies detected in Midwestern white-tailed deer (Odocoileus virginianus) by Western blot and ELISA

Anderson, T., DeJardin, A., Howe, D. K., Dubey, J. P. & Michalski, M. L., Apr 10 2007, In: Veterinary Parasitology. 145, 1-2, p. 152-155 4 p.

Research output: Contribution to journal › Article › peer-review

A new trivalent SnSAG surface antigen chimera for efficient detection of antibodies against Sarcocystis neurona and diagnosis of equine protozoal myeloencephalitis

Yeargan, M., de Assis Rocha, I., Morrow, J., Graves, A., Reed, S. M. & Howe, D. K., May 6 2015, In: Journal of Veterinary Diagnostic Investigation. 27, 3, p. 377-381 5 p.

Research output: Contribution to journal › Article › peer-review

The apicomplexan pathogen Neospora caninum inhibits host cell apoptosis in the absence of discernible NF-κB activation

Herman, R. K., Molestina, R. E., Sinai, A. P. & Howe, D. K., Sep 2007, In: Infection and Immunity. 75, 9, p. 4255-4262 8 p.

Research output: Contribution to journal › Article › peer-review

Partially protective vaccination permits the development of latency in a normally virulent strain of Toxoplasma gondii

Yap, G. S., Scharton-Kersten, T., Ferguson, D. J. P., Howe, D., Suzuki, Y. & Sher, A., 1998, In: Infection and Immunity. 66, 9, p. 4382-4388 7 p.

Research output: Contribution to journal › Article › peer-review

Differential roles for inner membrane complex proteins across Toxoplasma gondii and Sarcocystis neurona development

Dubey, R., Harrison, B., Dangoudoubiyam, S., Bandini, G., Cheng, K., Kosber, A., Agop-Nersesian, C., Howe, D. K., Samuelson, J., Ferguson, D. J. P. & Gubbels, M. J., Sep 1 2017, In: mSphere. 2, 5, e00409-17.

Research output: Contribution to journal › Article › peer-review

Investigation of SnSPR1, a novel and abundant surface protein of Sarcocystis neurona merozoites

Zhang, D. & Howe, D. K., Apr 15 2008, In: Veterinary Parasitology. 152, 3-4, p. 210-219 10 p.

Research output: Contribution to journal › Article › peer-review

Characterization of the oregon isolate of Neospora hughesi from a horse

Dubey, J. P., Liddell, S., Mattson, D., Speer, C. A., Howe, D. K. & Jenkins, M. C., 2001, In: Journal of Parasitology. 87, 2, p. 345-353 9 p.

Research output: Contribution to journal › Article › peer-review

Accurate antemortem diagnosis of equine protozoal myeloencephalitis (EPM) based on detecting intrathecal antibodies against sarcocystis neurona using the SnSAG2 and SnSAG4/3 ELISAs

Reed, S. M., Howe, D. K., Morrow, J. K., Graves, A., Yeargan, M. R., Johnson, A. L., Mackay, R. J., Furr, M., Saville, W. J. A. & Williams, N. M., Sep 2013, In: Journal of Veterinary Internal Medicine. 27, 5, p. 1193-1200 8 p.

Research output: Contribution to journal › Article › peer-review

Acute virulence in mice is associated with markers on chromosome VIII in Toxoplasma gondii

Howe, D. K., Summers, B. C. & David Sibley, L., 1996, In: Infection and Immunity. 64, 12, p. 5193-5198 6 p.

Research output: Contribution to journal › Article › peer-review

Investigation of the Immunopathogenesis of Equine Protozoal Myeloencephalitis (EPM)

de Assis Rocha, I. (PI) & Howe, D. (CoI)

Morris Animal Foundation

5/1/24 → 4/30/26

Project: Research project

Bumped Kinase Inhibitor for Toxoplasmosis and and Sarcocystosis

Howe, D. (PI) & Page, A. (CoPI)

University of Washington

6/1/20 → 5/31/26

Project: Research project

Evaluation of Sarcocystis Neurona Antigens for Development of Subunit Vaccines Against Equine Protozoal Myeloencephalitis

Howe, D. (PI) & Horohov, D. (CoI)

Fort Dodge Laboratories

4/1/01 → 3/31/07

Project: Research project

Genome Sequence for the Apicomplexan Sarcocystis Neurona

Howe, D. (PI) & Schardl, C. (CoI)

Cooperative State Research Education and Extension

9/1/09 → 8/31/13

Project: Research project

Advanced Genetic Technologies

Schardl, C. (PI) & Howe, D. (CoI)

Cooperative State Research Education and Extension

9/1/08 → 8/31/11

Project: Research project

KSEF KCF: Novel Therapeutic Approaches to Treatment of Parasitic Disease and Related Clinical Conditions

Tobin, T. (PI), Howe, D. (CoI) & Pauly, J. (CoI)

KY Science and Technology Co Inc

4/1/07 → 12/31/10

Project: Research project

Advanced Genetic Technologies

Schardl, C. (PI), Downie, A. (CoI), Ghabrial, S. (CoI), Howe, D. (CoI), Matthews, J. (CoI), McLeod, K. (CoI) & Timoney, J. (CoI)

Cooperative State Research Education and Extension

7/1/03 → 6/30/05

Project: Research project

Enhancing Genetic Analysis and Sequencing Facility

Schardl, C. (PI), Gan, S. (CoI), Howe, D. (CoI), Nagy, P. (CoI), Perry, S. (CoI) & Webb, B. (CoI)

US Department of Agriculture

1/1/02 → 12/31/04

Project: Research project

Identification and Characterization of Immunodominant Antigens from Sarcocystis neurona, the Primary Cause of EPM

Howe, D. (PI)

Amerman Family Foundation

1/1/01 → 12/31/05

Project: Research project