Richard King

Associated Departments

Scholars@UK

Voxel-wise insights into early Alzheimer’s disease pathology progression: the association with APOE and memory decline

for the Alzheimer’s Disease Neuroimaging Initiative, 2025, (Accepted/In press) In: GeroScience. e12019.

Research output: Contribution to journal › Article › peer-review

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume

Alzheimer’s Disease Neuroimaging Initiative (ADNI) & Australian Imaging Biomarkers and Lifestyle (AIBL) Study, Jun 2022, In: GeroScience. 44, 3, p. 1807-1823 17 p.

Research output: Contribution to journal › Article › peer-review

Dynamic proportional loss of functional connectivity revealed change of left superior frontal gyrus in subjective cognitive decline: an explanatory study based on Chinese and Western cohorts

for the Alzheimer’s Disease Neuroimaging Initiative, 2025, (Accepted/In press) In: GeroScience.

Research output: Contribution to journal › Article › peer-review

Local molecular and connectomic contributions of tau-related neurodegeneration

for the Alzheimer’s disease Neuroimaging Initiative (ADNI), Feb 2025, In: GeroScience. 47, 1, p. 227-246 20 p.

Research output: Contribution to journal › Article › peer-review

Complementary value of molecular, phenotypic, and functional aging biomarkers in dementia prediction

Alzheimer’s Disease Neuroimaging Initiative Consortium, Apr 2025, In: GeroScience. 47, 2, p. 2099-2118 20 p.

Research output: Contribution to journal › Article › peer-review

Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction

Alzheimer’s Disease Neuroimaging Initiative, Dec 2023, In: Communications Medicine. 3, 1, 49.

Research output: Contribution to journal › Article › peer-review

Impact of amyloid and cardiometabolic risk factors on prognostic capacity of plasma neurofilament light chain for neurodegeneration

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 2024, In: Alzheimer's Research and Therapy. 16, 1, 202.

Research output: Contribution to journal › Article › peer-review

Sex differences in interacting genetic and functional connectivity biomarkers in Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative Consortium, Dec 2024, In: GeroScience. 46, 6, p. 6071-6084 14 p.

Research output: Contribution to journal › Article › peer-review

Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort

Oka, T., Matsuzawa, Y., Tsuneyoshi, M., Nakamura, Y., Aoshima, K., Tsugawa, H., Weiner, M., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J., Shaw, L. M., Liu, E. & Montine, T. & 278 others, Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Harvey, D., Donohue, M., Bernstein, M., Fox, N., Thompson, P., Schuff, N., DeCArli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Householder, E., Reinwald, L. T., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Shen, L., Kelley, F., Kim, S., Nho, K., Kachaturian, Z., Frank, R., Snyder, P. J., Molchan, S., Kaye, J., Quinn, J., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Petersen, R., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Meyer, J. V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Morris, J. C., Carroll, M., Leon, S., Householder, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., de Toledo-Morrell, L., Shah, R. C., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D’Agostino, D., Kielb, S., Galvin, J. E., Pogorelec, D. M., Cerbone, B., Michel, C. A., Rusinek, H., de Leon, M. J., Glodzik, L., De Santi, S., Doraiswamy, P. M., Petrella, J. R., Wong, T. Z., Arnold, S. E., Karlawish, J. H., Wolk, D., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Mulnard, R. A., Thai, G., Mc Adams Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Arrastia, R. D., King, R., Weiner, M., Cook, K. M., DeVous, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Anderson, H. S., Swerdlow, R. H., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Matthews, B. R., Herring, S., Hunt, C., van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Kertesz, A., Rogers, J., Trost, D., Bernick, C., Munic, D., Kerwin, D., Mesulam, M. M., Lipowski, K., Wu, C. K., Johnson, N., Sadowsky, C., Martinez, W., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Frey, M., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Johnson, P. L., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Hudson, L., Fletcher, E., Carmichael, O., Olichney, J., DeCarli, C., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Santulli, R. B., Kitzmiller, T. J., Schwartz, E. S., Sink, K. M., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Mintzer, J., Spicer, K., Bachman, D., Finger, E., Pasternak, S., Rachinsky, I., Rogers, J., Kertesz, A., Drost, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ponto, L. L. B., Shim, H., Smith, K. E., Relkin, N., Chaing, G., Raudin, L., Smith, A., Fargher, K. & Raj, B. A., Dec 2024, In: Scientific Reports. 14, 1, 6797.

Research output: Contribution to journal › Article › peer-review

Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease

for the ADNI, Jun 2023, In: International Journal of Geriatric Psychiatry. 38, 6, e5952.

Research output: Contribution to journal › Article › peer-review

A data-driven examination of apathy and depressive symptoms in dementia with independent replication

for the Alzheimer’s Disease Neuroimaging Initiative, Jan 1 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 1, e12398.

Research output: Contribution to journal › Article › peer-review

Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease

Alzheimer’s Disease Neuroimaging Initiative & the Swedish BioFinder Study, Dec 2020, In: Nature Communications. 11, 1, 2612.

Research output: Contribution to journal › Article › peer-review

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dominantly Inherited Alzheimer Network (DIAN) Study Group & Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group, Dec 2021, In: Nature Communications. 12, 1, 5346.

Research output: Contribution to journal › Article › peer-review

A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure

iSTAGING Consortium, Baltimore Longitudinal Study of Aging (BLSA) & Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 2021, In: Nature Communications. 12, 1, 7065.

Research output: Contribution to journal › Article › peer-review

Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dec 2022, In: Nature Communications. 13, 1, 1495.

Research output: Contribution to journal › Article › peer-review

The trend of disruption in the functional brain network topology of Alzheimer’s disease

for the Alzheimer’s Disease Neuroimaging Initiative, Dec 2022, In: Scientific Reports. 12, 1, 14998.

Research output: Contribution to journal › Article › peer-review

An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer’s disease

Alzheimer’s Disease Neuroimaging Initiative, Jul 2022, In: Nature Aging. 2, 7, p. 616-634 19 p.

Research output: Contribution to journal › Article › peer-review

Glucose metabolism patterns: A potential index to characterize brain ageing and predict high conversion risk into cognitive impairment

for the Alzheimer’s Disease Neuroimaging Initiative, Aug 2022, In: GeroScience. 44, 4, p. 2319-2336 18 p.

Research output: Contribution to journal › Article › peer-review

Author Correction: Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease (Nature Communications, (2020), 11, 1, (2612), 10.1038/s41467-020-15701-2)

Alzheimer’s Disease Neuroimaging Initiative & the Swedish BioFinder Study, Dec 1 2021, In: Nature Communications. 12, 1, 4862.

Research output: Contribution to journal › Comment/debate

Tau-Atrophy Variability Reveals Phenotypic Heterogeneity in Alzheimer's Disease

Alzheimer’s Disease Neuroimaging Initiative, Nov 2021, In: Annals of Neurology. 90, 5, p. 751-762 12 p.

Research output: Contribution to journal › Article › peer-review

Clinical Core: University of Kentucky Alzheimer's Disease Research Center

Jicha, G. (PI), Caudill, T. (CoI), Coskun, E. (CoI), Harp, J. (CoI), Jiang, Y. (CoI), King, R. (CoI), Schmitt, F. (CoI) & Van Eldik, L. (CoI)