Associated Departments

Veterinary Science

Scholars@UK

The probiotic Lacticaseibacillus rhamnosus GG supplementation reduces Salmonella load and modulates growth, intestinal morphology, gut microbiota, and immune responses in chickens

Closs, G., Bhandari, M., Helmy, Y. A., Kathayat, D., Lokesh, D., Jung, K., Suazo, I. D., Srivastava, V., Deblais, L. & Rajashekara, G., May 2025, In: Infection and Immunity. 93, 5

Research output: Contribution to journal › Article › peer-review

Genomic and Computational Analysis Unveils Bacteriocin Based Therapeutics against Clinical Mastitis Pathogens in Dairy Cows

Hasnat, S., Rahman, M. M., Yeasmin, F., Jubair, M., Helmy, Y. A., Islam, T. & Hoque, M. N., 2025, (Accepted/In press) In: Probiotics and Antimicrobial Proteins. 564056.

Research output: Contribution to journal › Article › peer-review

Eco-friendly synthesis of Ag/CeO2 and CuO/CeO2 nanocomposites using Curcuma longa extract and assessment of their antioxidant, antifungal, and cytotoxic activities

Elattar, K. M., Ghoniem, A. A., Al-Otibi, F. O., Fakhouri, A. S., Helmy, Y. A., Saber, W. E. I. A., Hassan, M. A. E. & Elsayed, A., Apr 17 2025, In: RSC Advances. 15, 16, p. 12100-12116 17 p.

Research output: Contribution to journal › Article › peer-review

Chemical, Physical, Microbial, and Sensory Properties of Innovative Sesame Milk Kefir, Focusing on the Ultrastructure of Kefir Grains

Abou Ayana, I. A. A., Al-Otibi, F. O., Elgarhy, M. R., Omar, M. M., EL-Abbassy, M. Z., Khalifa, S. A., Helmy, Y. A. & Saber, W. E. I. A., Mar 4 2025, In: ACS Omega. 10, 8, p. 7752-7769 18 p.

Research output: Contribution to journal › Article › peer-review

Phenotypic and genotypic characterization of antimicrobial resistance and virulence profiles of Salmonella enterica serotypes isolated from necropsied horses in Kentucky

Kabir, A., Kelley, W. G., Glover, C., Erol, E. & Helmy, Y. A., Mar 2025, In: Microbiology spectrum. 13, 3

Research output: Contribution to journal › Article › peer-review

Revolutionizing Nanovaccines: A New Era of Immunization

Saleh, M., El-Moghazy, A., Elgohary, A. H., Saber, W. E. I. A. & Helmy, Y. A., Feb 2025, In: Vaccines. 13, 2, 126.

Research output: Contribution to journal › Review article › peer-review

Alternaria radicina; unveiling the cause, spread, and molecular basis of a novel coriander leaf blight disease in Egypt

Ghoneem, K. M., Rashad, E. M., Al-Askar, A. A., Helmy, Y. A., El-Gamal, S. M. A., Ibrahim, S. D. & Saber, W. E. I. A., Jan 15 2025, In: Heliyon. 11, 1, e41081.

Research output: Contribution to journal › Article › peer-review

Antimicrobial resistance and whole genome sequencing of novel sequence types of Enterococcus faecalis, Enterococcus faecium, and Enterococcus durans isolated from livestock

El Zowalaty, M. E., Lamichhane, B., Falgenhauer, L., Mowlaboccus, S., Zishiri, O. T., Forsythe, S. & Hemly, Y. A., Dec 2023, In: Scientific Reports. 13, 1, 18609.

Research output: Contribution to journal › Article › peer-review

Simplex-lattice design and decision tree optimization of endophytic Trichoderma-multi-walled carbon nanotube composite for enhanced methylene blue removal

Abo-Neima, S. E., Elsehly, E. M., Al-Otibi, F. O., El-Metwally, M. M., Helmy, Y. A., Eldadamony, N. M., Saber, W. E. I. A. & El-Morsi, A. A., Nov 15 2024, In: Heliyon. 10, 21, e39949.

Research output: Contribution to journal › Article › peer-review

Draft genome sequence analysis of multidrug-resistant Salmonella enterica subsp. enterica serovar Mbandaka harboring colistin resistance gene mcr-9.1 isolated from foals in Kentucky, USA

Helmy, Y. A., Kabir, A., Saleh, M., Kennedy, L. A., Burns, L. & Johnson, B., Oct 7 2024, (E-pub ahead of print) In: Microbiology Resource Announcements. p. e0073724

Research output: Contribution to journal › Article › peer-review

Enhanced biochemical, microbial, and ultrastructural attributes of reduced-fat labneh through innovative microalgae integration

Refaey, M. M., Al-Otibi, F. O., El-Khateeb, A. Y., Helmy, Y. A., Saber, W. E. I. A. & Zalma, S. A., Dec 2024, In: Scientific Reports. 14, 1, 21188.

Research output: Contribution to journal › Article › peer-review

Antimicrobial Resistance in Equines: A Growing Threat to Horse Health and Beyond—A Comprehensive Review

Kabir, A., Lamichhane, B., Habib, T., Adams, A., El-Sheikh Ali, H., Slovis, N. M., Troedsson, M. H. T. & Helmy, Y. A., Aug 2024, In: Antibiotics. 13, 8, 713.

Research output: Contribution to journal › Review article › peer-review

Molecular Characterization of Multidrug-Resistant and Extended-Spectrum β-Lactamases-Producing Salmonella enterica Serovars Enteritidis and Typhimurium Isolated from Raw Meat in Retail Markets

Rahman, M. M., Hossain, H., Chowdhury, M. S. R., Hossain, M. M., Saleh, A., Binsuwaidan, R., Noreddin, A., Helmy, Y. A. & El Zowalaty, M. E., Jul 2024, In: Antibiotics. 13, 7, 586.

Research output: Contribution to journal › Article › peer-review

Artificial Intelligence-Powered Optimization and Milk Permeate Upcycling for Innovative Sesame Milk with Enhanced Probiotic Viability and Sensory Appeal

Abou Ayana, I. A. A., Elgarhy, M. R., Al-Otibi, F. O., Omar, M. M., El-Abbassy, M. Z., Khalifa, S. A., Helmy, Y. A. & Saber, W. E. I. A., Jun 11 2024, In: ACS Omega. 9, 23, p. 25189-25202 14 p.

Research output: Contribution to journal › Article › peer-review

Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control of Campylobacter jejuni in chickens

Deblais, L., Drozd, M., Kumar, A., Antwi, J., Fuchs, J., Khupse, R., Helmy, Y. A. & Rajashekara, G., 2024, In: Frontiers in Microbiology. 15, 1342573.

Research output: Contribution to journal › Article › peer-review

Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives

Abouelela, M. E. & Helmy, Y. A., Mar 2024, In: Microorganisms. 12, 3, 430.

Research output: Contribution to journal › Review article › peer-review

Draft genome sequences of Bacillus licheniformis strains MEZBL63 and MEZBL64 harboring the lichenysin toxin operon isolated from livestock in South Africa

El Zowalaty, M. E., Falgenhauer, L., Ashour, H. M., Zishiri, O. T., Forsythe, S. & Helmy, Y. A., Mar 2024, In: Microbiology Resource Announcements. 13, 3

Research output: Contribution to journal › Article › peer-review

Turmeric extract-mediated biogenic synthesis of Ag@SeO2 magnetic nanoparticles: characterization, optimization, antibacterial and antioxidant activities

Ghoniem, A. A., Elattar, K. M., Al-Otibi, F. O., Elsayed, A., El-Hersh, M. S., El-Khateeb, A. Y., Helmy, Y. A. & Saber, W. E. I. A., Feb 27 2024, In: RSC Advances. 14, 10, p. 7088-7111 24 p.

Research output: Contribution to journal › Article › peer-review

Advances in Poultry Vaccines: Leveraging Biotechnology for Improving Vaccine Development, Stability, and Delivery

Abdelaziz, K., Helmy, Y. A., Yitbarek, A., Hodgins, D. C., Sharafeldin, T. A. & Selim, M. S. H., Feb 2024, In: Vaccines. 12, 2, 134.

Research output: Contribution to journal › Review article › peer-review

Salmonellosis: An Overview of Epidemiology, Pathogenesis, and Innovative Approaches to Mitigate the Antimicrobial Resistant Infections

Lamichhane, B., Mawad, A. M. M., Saleh, M., Kelley, W. G., Harrington, P. J., Lovestad, C. W., Amezcua, J., Sarhan, M. M., El Zowalaty, M. E., Ramadan, H., Morgan, M. & Helmy, Y. A., Jan 2024, In: Antibiotics. 13, 1, 76.

Research output: Contribution to journal › Review article › peer-review

Development of Novel Small Molecules as Antibiotic Alternatives for the Control of Rhodococcus Equi in Foals

Helmy, Y. A. (PI)

Morris Animal Foundation

3/1/25 → 2/28/26

Project: Research project

KL2 Scholar Scope - Probiotics-Derived Bioactive Molecules as Alternatives to Antibiotics to Mitigate Antibiotic-Resistant Campylobacter Infections in Humans

Helmy, Y. A. (PI) & Kelly, T. (CoI)

National Center for Advancing Translational Sciences

2/1/24 → 6/30/25

Project: Research project

Yosra Mohamed (Helmy) Scope: COBRE in Pharmaceutical Research and Innovation

Helmy, Y. A. (PI) & Thorson, J. (CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/26

Project: Research project

Novel Therapeutics for the Control of Multidrug-resistant Rhodococcus Equi in Foals

Helmy, Y. A. (PI)

American Quarter Horse Foundation

10/1/24 → 9/30/25

Project: Research project

Kentucky Center for Clinical and Translational Science - Institutional Career Development Core

Kelly, T. (PI), Barry-Hundeyin, M. (CoI), Curry, T. (CoI), DiPaola, R. (CoI), Evers, B. M. (CoI), Giannone, P. (CoI), Guy, R. K. (CoI), Helmy, Y. A. (CoI), Jicha, G. (CoI), Kern, P. (CoI), King, V. (CoI), Lephart, S. (CoI), Liu, J. (CoI), Talbert, J. (CoI), Trout, A. (CoI), Williams, L. (CoI), Bush, M. (CoPI), Arnett, D. (Former CoI), Duncan, M. (Former CoI), Heath, E. (Former CoI), Lacy Leigh, M. (Former CoI), McLouth, L. (Former CoI), Roberts, J. (Former CoI), Samaan, M. (Former CoI) & Supinski, G. (Former CoI)

National Center for Advancing Translational Sciences

8/15/16 → 6/30/26

Project: Research project

KL2 scope - Probiotics-Derived Bioactive Molecules as Alternatives to Antibiotics to Mitigate Antibiotic-resistant Campylobacter Infections in Humans

Helmy, Y. A. (PI) & Kelly, T. (CoI)

National Center for Advancing Translational Sciences

2/1/24 → 6/30/24

Project: Research project

COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI), Helmy, Y. A. (CoI), Jaramillo, A. (CoI), She, Q.-B. (CoI), Adams, V. (Former CoI), Alam, M. (Former CoI), Awuah, S. (Former CoI), Bardo, M. (Former CoI), Bauer, B. (Former CoI), Burgess, D. (Former CoI), Czuba, L. (Former CoI), Daugherty, A. (Former CoI), Dwoskin, L. (Former CoI), Feola, D. (Former CoI), Garneau-Tsodikova, S. (Former CoI), Gensel, J. (Former CoI), Glazer, E. (Former CoI), Grady, M. (Former CoI), Graf, G. (Former CoI), Kapur, N. (Former CoI), Kolesar, J. (Former CoI), Korotkov, K. (Former CoI), Korotkova, N. (Former CoI), Leggas, M. (Former CoI), Mahmoud, K. A. (Former CoI), McLaurin, K. (Former CoI), Messaoudi Powers, I. (Former CoI), Nikolajczyk, B. (Former CoI), Ortinski, P. (Former CoI), Pack, D. (Former CoI), Park, J. (Former CoI), Prisinzano, T. (Former CoI), Richards, C. (Former CoI), Rohr, J. (Former CoI), Sen, P. (Former CoI), Shaffer, C. (Former CoI), Stevenson, B. (Former CoI), Sturgill, J. (Former CoI), Sviripa, V. (Former CoI), Tidgewell, K. (Former CoI), Tiruvannamalai Annam, R. (Former CoI), Turner, J. (Former CoI), Van Lanen, S. (Former CoI), Venditto, V. (Former CoI), Watt, D. (Former CoI), Webb, N. (Former CoI) & Zhan, C.-G. (Former CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/26

Project: Research project

Carryforward: COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI), Adams, V. (CoI), Awuah, S. (CoI), Bardo, M. (CoI), Bauer, B. (CoI), Czuba, L. (CoI), Dwoskin, L. (CoI), Feola, D. (CoI), Gensel, J. (CoI), Grady, M. (CoI), Graf, G. (CoI), Jaramillo, A. (CoI), Kapur, N. (CoI), Mahmoud, K. A. (CoI), Messaoudi Powers, I. (CoI), Nikolajczyk, B. (CoI), Ortinski, P. (CoI), Pack, D. (CoI), Park, J. (CoI), Prisinzano, T. (CoI), Rohr, J. (CoI), She, Q.-B. (CoI), Stevenson, B. (CoI), Tidgewell, K. (CoI), Tiruvannamalai Annam, R. (CoI), Turner, J. (CoI), Van Lanen, S. (CoI), Venditto, V. (CoI), Zhan, C.-G. (CoI), Alam, M. (Former CoI), Burgess, D. (Former CoI), Daugherty, A. (Former CoI), Garneau-Tsodikova, S. (Former CoI), Glazer, E. (Former CoI), Helmy, Y. A. (Former CoI), Kolesar, J. (Former CoI), Korotkov, K. (Former CoI), Korotkova, N. (Former CoI), Leggas, M. (Former CoI), Richards, C. (Former CoI), Sen, P. (Former CoI), Shaffer, C. (Former CoI), Sturgill, J. (Former CoI), Sviripa, V. (Former CoI), Watt, D. (Former CoI) & Webb, N. (Former CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/24

Project: Research project

Kentucky Center for Clinical and Translational Science - Institutional Career Development Core

Kelly, T. (PI), Barry-Hundeyin, M. (CoI), Curry, T. (CoI), DiPaola, R. (CoI), Evers, B. M. (CoI), Giannone, P. (CoI), Guy, R. K. (CoI), Helmy, Y. A. (CoI), Jicha, G. (CoI), Kern, P. (CoI), King, V. (CoI), Lephart, S. (CoI), Liu, J. (CoI), Talbert, J. (CoI), Trout, A. (CoI), Williams, L. (CoI), Arnett, D. (Former CoI), Duncan, M. (Former CoI), Heath, E. (Former CoI), Lacy Leigh, M. (Former CoI), McLouth, L. (Former CoI), Roberts, J. (Former CoI), Samaan, M. (Former CoI) & Supinski, G. (Former CoI)

National Center for Advancing Translational Sciences

8/15/16 → 6/30/24

Project: Research project

Probiotic Nissle E. coli 1917 as antibiotic-alternative to combat antibiotic-resistant Campylobacter in the food chain

Helmy, Y. A. (PI), Messaoudi Powers, I. (CoI) & Thorson, J. (CoI)

National Institute of Food and Agriculture

8/1/23 → 7/31/26

Project: Research project

Evaluate the efficacy of probiotics on colonization and pathogenicity of Campylobacter jejuni

Helmy, Y. A. (PI) & Messaoudi Powers, I. (CoPI)

7/1/22 → 12/31/22

Project: Research project

COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI), Adams, V. (CoI), Awuah, S. (CoI), Bardo, M. (CoI), Bauer, B. (CoI), Czuba, L. (CoI), Dwoskin, L. (CoI), Feola, D. (CoI), Gensel, J. (CoI), Grady, M. (CoI), Graf, G. (CoI), Jaramillo, A. (CoI), Kapur, N. (CoI), Mahmoud, K. A. (CoI), McLaurin, K. (CoI), Messaoudi Powers, I. (CoI), Nikolajczyk, B. (CoI), Ortinski, P. (CoI), Pack, D. (CoI), Park, J. (CoI), Prisinzano, T. (CoI), Rohr, J. (CoI), She, Q.-B. (CoI), Stevenson, B. (CoI), Tidgewell, K. (CoI), Turner, J. (CoI), Van Lanen, S. (CoI), Venditto, V. (CoI), Zhan, C.-G. (CoI), Alam, M. (Former CoI), Burgess, D. (Former CoI), Daugherty, A. (Former CoI), Garneau-Tsodikova, S. (Former CoI), Glazer, E. (Former CoI), Helmy, Y. A. (Former CoI), Kolesar, J. (Former CoI), Korotkov, K. (Former CoI), Korotkova, N. (Former CoI), Leggas, M. (Former CoI), Richards, C. (Former CoI), Sen, P. (Former CoI), Shaffer, C. (Former CoI), Sturgill, J. (Former CoI), Sviripa, V. (Former CoI), Tiruvannamalai Annam, R. (Former CoI), Watt, D. (Former CoI) & Webb, N. (Former CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/24

Project: Research project

Pilot Project-Yosra Mohamed :COBRE in Pharmaceutical Research and Innovation

Helmy, Y. A. (PI) & Thorson, J. (CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/23

Project: Research project

COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI), Adams, V. (CoI), Alam, M. (CoI), Burgess, D. (CoI), Czuba, L. (CoI), Dwoskin, L. (CoI), Feola, D. (CoI), Garneau-Tsodikova, S. (CoI), Gensel, J. (CoI), Grady, M. (CoI), Graf, G. (CoI), Helmy, Y. A. (CoI), Korotkov, K. (CoI), Mahmoud, K. A. (CoI), Nikolajczyk, B. (CoI), Pack, D. (CoI), Park, J. (CoI), Prisinzano, T. (CoI), Shaffer, C. (CoI), Stevenson, B. (CoI), Tiruvannamalai Annam, R. (CoI), Van Lanen, S. (CoI), Venditto, V. (CoI), Zhan, C.-G. (CoI), Awuah, S. (Former CoI), Daugherty, A. (Former CoI), Glazer, E. (Former CoI), Kolesar, J. (Former CoI), Korotkova, N. (Former CoI), Leggas, M. (Former CoI), Richards, C. (Former CoI), Rohr, J. (Former CoI), Sen, P. (Former CoI), Sturgill, J. (Former CoI), Sviripa, V. (Former CoI), Watt, D. (Former CoI) & Webb, N. (Former CoI)

National Institute of General Medical Sciences

3/1/20 → 1/31/23

Project: Research project