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Leadership Meet the Administrative Team Departments and Units Aute et fugiat ad est cupidatat esse laborum dolor ex anim anim cillum cillum exercitation culpa. Our Experts Aute et fugiat ad est cupidatat esse laborum dolor ex anim anim cillum cillum exercitation culpa.State Administration Get contact information for Extension administrative personnel by operational area and their respective support personnel. Area Extension Directors Get contact information for the Area Extension Directors (AEDs) County Extension Personnel Aute et fugiat ad est cupidatat esse laborum dolor ex anim anim cillum cillum exercitation culpa.
Ling Yuan
Regular Faculty
Associated Departments
Scholars@UK
Mitogen-activated protein kinase-mediated regulation of plant specialized metabolism
Zhou, Y., Singh, S. K., Patra, B., Liu, Y., Pattanaik, S. & Yuan, L., Jan 10 2025, In: Journal of Experimental Botany. 76, 2, p. 262-276 15 p.Research output: Contribution to journal › Review article › peer-review
Transcriptome analysis and functional identification of transfer RNA-derived fragments in grape leaves exposed to UV-C radiation
Li, Y., Kong, L., Mu, H., Wang, J., Li, F., Kuang, Y., Duan, W., Fan, P., Yuan, L., Liang, Z. & Wang, L., Feb 2025, In: Plant Physiology and Biochemistry. 219, 109425.Research output: Contribution to journal › Article › peer-review
An overview of the regulation of specialized metabolism in tobacco
Wu, X., Singh, S. K., Patra, B., Wang, J., Pattanaik, S. & Yuan, L., Mar 2025, In: Current Plant Biology. 41, 100431.Research output: Contribution to journal › Review article › peer-review
Phase separation of MYB73 regulates seed oil biosynthesis in Arabidopsis
Yang, Y., Kong, Q., Ma, Z., Lim, P. K., Singh, S. K., Pattanaik, S., Mutwil, M., Miao, Y., Yuan, L. & Ma, W., Feb 2025, In: Plant Physiology. 197, 2, kiae674.Research output: Contribution to journal › Article › peer-review
ZINC FINGER PROTEIN2 suppresses funiculus lignification to ensure seed loading efficiency in Arabidopsis
Low, P. M., Kong, Q., Blaschek, L., Ma, Z., Lim, P. K., Yang, Y., Quek, T., Lim, C. J. R., Singh, S. K., Crocoll, C., Engquist, E., Thorsen, J. S., Pattanaik, S., Tee, W. T., Mutwil, M., Miao, Y., Yuan, L., Xu, D., Persson, S. & Ma, W., Jun 23 2025, In: Developmental Cell. 60, 12, p. 1719-1729.e6Research output: Contribution to journal › Article › peer-review
Transcriptional Reprogramming Deploys a Compartmentalized ‘Timebomb’ in Catharanthus roseus to Fend Off Chewing Herbivores
Liu, Y., Shi, J., Patra, B., Singh, S. K., Wu, X., Lyu, R., Liu, X., Li, Y., Wang, Y., Zhou, X., Pattanaik, S. & Yuan, L., May 2025, In: Plant, Cell and Environment. 48, 5, p. 3236-3256 21 p.Research output: Contribution to journal › Article › peer-review
Characterization and Molecular Engineering of a N-Methyltransferase from Edible Nelumbo nucifera Leaves Involved in Nuciferine Biosynthesis
Chen, S., Wang, Z., Dong, G. Q., Zhao, H., Zhu, Y., Liu, Y., Yuan, L., Jiang, J., Liu, X. J., Liu, A. & Yu, Y., 2024, (Accepted/In press) In: Journal of Agricultural and Food Chemistry.Research output: Contribution to journal › Article › peer-review
The evolutionary advantage of artemisinin production by Artemisia annua
Yin, Q., Xiang, L., Han, X., Zhang, Y., Lyu, R., Yuan, L. & Chen, S., Feb 2025, In: Trends in Plant Science. 30, 2, p. 213-226 14 p.Research output: Contribution to journal › Review article › peer-review
Harnessing the spatial and transcriptional regulation of monoterpenoid indole alkaloid metabolism in Alstonia scholaris leads to the identification of broad geissoschizine cyclase activities
Méteignier, L. V., Szwarc, S., Barunava, P., Durand, M., Zamar, D. L., Birer Williams, C., Gautron, N., Dutilleul, C., Koudounas, K., Lezin, E., Perrot, T., Oudin, A., Pateyron, S., Delannoy, E., Brunaud, V., Lanoue, A., Abbasi, B. H., St-Pierre, B., Jensen, M. K. & Papon, N. & 6 others, , Feb 2025, In: Plant Physiology and Biochemistry. 219, 109363.Research output: Contribution to journal › Article › peer-review
A cytosine analogue 5-azacitidine improves the accumulation of licochalcone A in licorice Glycyrrhiza inflata
Ma, X., Jiang, N., Fu, J., Li, Y., Zhou, L., Yuan, L., Wang, Y. & Li, Y., Jan 2024, In: Journal of Plant Physiology. 292, 154145.Research output: Contribution to journal › Article › peer-review
Integrated metabolomic and transcriptomic analysis provides insights into the flavonoid formation in different Glycyrrhiza species
Li, Y., Xie, Z., Huang, Y., Zeng, J., Yang, C., Yuan, L., Wang, Y. & Li, Y., Feb 2024, In: Industrial Crops and Products. 208, 117796.Research output: Contribution to journal › Article › peer-review
A Cotyledon-based Virus-Induced Gene Silencing (Cotyledon-VIGS) approach to study specialized metabolism in medicinal plants
Liu, Y., Lyu, R., Singleton, J. J., Patra, B., Pattanaik, S. & Yuan, L., Dec 2024, In: Plant Methods. 20, 1, 26.Research output: Contribution to journal › Article › peer-review
Improving digestibility of sorghum proteins by CRISPR/Cas9-based genome editing
Li, X., Liu, W., Wang, G., Sun, S. S. M., Yuan, L. & Wang, J., Jan 1 2024, In: Food and Energy Security. 13, 1, e506.Research output: Contribution to journal › Article › peer-review
VvBBX44 and VvMYBA1 form a regulatory feedback loop to balance anthocyanin biosynthesis in grape
Liu, W., Mu, H., Yuan, L., Li, Y., Li, Y., Li, S., Ren, C., Duan, W., Fan, P., Dai, Z., Zhou, Y., Liang, Z., Li, S. & Wang, L., Oct 1 2023, In: Horticulture Research. 10, 10, uhad176.Research output: Contribution to journal › Article › peer-review
MYB30 and MYB14 form a repressor-activator module with WRKY8 that controls stilbene biosynthesis in grapevine
Mu, H., Li, Y., Yuan, L., Jiang, J., Wei, Y., Duan, W., Fan, P., Li, S., Liang, Z. & Wang, L., Jan 2023, In: Plant Cell. 35, 1, p. 552-573 22 p.Research output: Contribution to journal › Article › peer-review
Genome-Wide Identification of SnRK1 Catalytic α Subunit and FLZ Proteins in Glycyrrhiza inflata Bat. Highlights Their Potential Roles in Licorice Growth and Abiotic Stress Responses
Yang, C., Shi, G., Li, Y., Luo, M., Wang, H., Wang, J., Yuan, L., Wang, Y. & Li, Y., Jan 2023, In: International Journal of Molecular Sciences. 24, 1, 121.Research output: Contribution to journal › Article › peer-review
Histone Deacetylase GiSRT2 Negatively Regulates Flavonoid Biosynthesis in Glycyrrhiza inflata
Zeng, J., Huang, Y., Zhou, L., Liang, X., Yang, C., Wang, H., Yuan, L., Wang, Y. & Li, Y., Jun 2023, In: Cells. 12, 11, 1501.Research output: Contribution to journal › Article › peer-review
The class B heat shock factor HSFB1 regulates heat tolerance in grapevine
Chen, H., Liu, X., Li, S., Yuan, L., Mu, H., Wang, Y., Li, Y., Duan, W., Fan, P., Liang, Z. & Wang, L., Mar 1 2023, In: Horticulture Research. 10, 3, uhad001.Research output: Contribution to journal › Article › peer-review
Light regulation of the biosynthesis of phenolics, terpenoids, and alkaloids in plants
Liu, Y., Singh, S. K., Pattanaik, S., Wang, H. & Yuan, L., Oct 18 2023, In: Communications Biology. 6, 1, p. 1055Research output: Contribution to journal › Review article › peer-review
Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr
Liu, Y., Song, Y., Zeng, S., Patra, B., Yuan, L. & Wang, Y., May 2018, In: Physiologia Plantarum. 163, 1, p. 73-87 15 p.Research output: Contribution to journal › Article › peer-review
FY25 Artesunate as Treatment for Childhood Acute Myeloid Leukemia C4935
Richards, C. (PI), Badgett, J. (CoI), Hill, K. (CoI), Ji, H. (CoI) & Yuan, L. (CoI)
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
Cigar Reference Products Program
Chambers, O. (PI), Fisher, A. (CoI), Fisher, C. (CoI), Ji, H. (CoI), McNees, C. (CoI), Shelton, B. (CoI) & Yuan, L. (CoI)
2/1/20 → 1/31/25
Project: Research project
FY24 Artesunate as Treatment for Childhood Acute Myeloid Leukemia
Kolesar, J. (PI), Badgett, J. (CoI), Hill, K. (CoI), Ji, H. (CoI) & Yuan, L. (CoI)
KY Cabinet for Health and Family Services
7/1/22 → 6/30/24
Project: Research project
Cigar Reference Products Program
Chambers, O. (PI), Fisher, A. (CoI), Fisher, C. (CoI), Ji, H. (CoI), McNees, C. (CoI), Shelton, B. (CoI) & Yuan, L. (CoI)
2/1/20 → 1/31/24
Project: Research project
High-throughput screening for fast neutron-induced mutations in the tobacco CBT-ol synthase gene using Illumina amplicon sequencing
Zaitlin, D. (PI), Farman, M. (CoI), Miller, R. (CoI), Wagner, G. (CoI) & Yuan, L. (CoI)
9/12/13 → 9/11/20
Project: Research project
BAT GWTobacco1
Wagner, G. (PI), Mihaylova-Kroumova, A. (CoI), Zaitlin, D. (CoI) & Yuan, L. (Former CoI)
9/12/13 → 12/31/21
Project: Research project
Production of Abietic Acid and Other Potentially-Useful, Related Diterpenes in Tobacco Trichomes
Chappell, J. (PI), Tang, G. (CoI), Wagner, G. (CoI) & Yuan, L. (CoI)
4/1/08 → 12/31/11
Project: Research project
Production of Abietic Acid and Other Potentially-Useful, Related Diterpenes in Tobacco Trichomes
Wagner, G. (PI), Chappell, J. (CoI), Tang, G. (CoI) & Yuan, L. (CoI)
4/1/08 → 12/31/11
Project: Research project
Novel Approach to Microbial Hydrogen Production
Yuan, L. (PI)
8/1/06 → 4/30/07
Project: Research project
FY23 Artesunate as Treatment for Childhood Acute Myeloid Leukemia
Kolesar, J. (PI), Badgett, J. (CoI), Ellingson, S. (CoI), Hill, K. (CoI), Ji, H. (CoI) & Yuan, L. (CoI)
KY Cabinet for Health and Family Services
7/1/22 → 6/30/23
Project: Research project
ARS/SCA: Tall Fescue Characteristics
Yuan, L. (PI), Bush, L. (CoI) & Ji, H. (CoI)
8/1/14 → 4/30/18
Project: Research project
KY EPSCoR: Powering the Kentucky Bioeconomy for a Sustainable Future (Yuan Scope)
Yuan, L. (PI)
KY Council on Postsecondary Education
6/1/14 → 12/30/18
Project: Research project
Scope: Smokeless Tobacco Reference Product Development, Distribution and Research
Durbin, E. B. (PI), Chambers, O. (CoI), Fisher, A. (CoI), Ji, H. (CoI), Moe, L. (CoI), Shelton, B. (CoI), Yuan, L. (CoI) & Canete, S. (Former CoI)
3/1/16 → 2/29/20
Project: Research project
Scope: Smokeless Tobacco Reference Product Development, Distribution and Research
Shelton, B. (PI), Chambers, O. (CoI), Durbin, E. B. (CoI), Fisher, A. (CoI), Ji, H. (CoI), Moe, L. (CoI), Yuan, L. (CoI) & Canete, S. (Former CoI)
3/1/16 → 2/29/20
Project: Research project